This is an inherited disorder with no symptoms. It does not cause abnormal bleeding in the affected person, but the blood takes longer than normal to clot (coagulate) in a test tube. It results from a deficiency of the plasma protein factor XII.
Causes, incidence, and risk factors:
Factor XII deficiency is a rare hereditary disorder that is usually found when clotting tests are done for routine screening. It is not associated with abnormal bleeding.
Review Date: 4/15/2005
Reviewed By: Rita Nanda, MD, Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.
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