Unilateral obstructive uropathy occurs when urine cannot drain through one of the tubes that carries urine from the kidney to the bladder. Urine backs up and causes kidney swelling (hydronephrosis). This condition is usually caused by a blockage from ureteral or kidney stones. Risks for unilateral obstructive uropathy include ureteral stones and tumors, kidney stones, and tumors in surrounding structures such as uterus, cervix, or lymph nodes. The disorder damages structures of the urinary tract. It may result in permanent damage to the kidney and may be a cause of hypertension. It usually does not cause kidney failure because the second kidney continues to function. Chronic unilateral obstructive uropathy occurs in approximately 5 out of every 1,000 people.
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