Chylomicronemia syndrome

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Overview

Symptoms

Treatment

Prevention

Chylomicronemia syndrome

Definition:

Chylomicronemia syndrome is an inherited disorder in which abnormal lipid (fat) metabolism causes chylomicrons (a type of lipids) to accumulate to massive levels in the blood.

Alternative Names:

Familial Lipoprotein Lipase Deficiency

Causes, incidence, and risk factors:

Chylomicronemia syndrome results from impaired or absent lipoprotein lipase (LPL), an enzyme in fat and muscle responsible for the breakdown of certain lipids. In addition to familial lipoprotein lipase deficiency, a large accumulation of chylomicrons may also be seen in people with familial apoprotein CII deficiency.

Review Date: 6/3/2005
Reviewed By: Thomas A. Owens, M.D., Departments of Internal Medicine and Pediatrics, Duke University Medical Center, Durham, NC. Review provided by VeriMed Healthcare Network.

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